N1-Guanyl-1,7-diaminoheptane,biosearch,G-100-10

描述：Biosearch Technologies專業(yè)性熒光定量 PCR 探針合成及標(biāo)記服務(wù)公司，提供與世界上各種熒光定量PCR儀配套的探標(biāo)記方式及熒光素。

更新時(shí)間：2015-06-24

訪問(wèn)次數(shù)：1738

廠商性質(zhì)：代理商

聯(lián)系我們留言詢價(jià)

詳情介紹

N1-Guanyl-1,7-diaminoheptane （GC7）

N1-Guanyl-1,7-Diaminoheptane, also known as GC7, is the most efficient inhibitor of deoxyhypusine synthase （DHS） known. As a competitive inhibitor it binds to the active site of DHS and prevents the first step in the post-translational conversion of a single lysine to hypusine in translation initiation factor 5A （eIF5A）. The modification is essential for sustained cell growth. GC7 acts on purified DHS and penetrates cells well to inhibit DHS inside the cell. GC7 has been used as cell cycle synchronizing reagent.