Athens Research（以下簡稱“AR"）是一家專注于為生命科學研究提供高可靠性工具與定制化解決方案的生物科技公司。我們始終相信，“科研的每一步突破，都始于精準的工具"——因此，AR以“賦能科研效率，降低實驗不確定性"為核心使命，深耕抗體開發(fā)、功能試劑盒研發(fā)、細胞培養(yǎng)基優(yōu)化及定制化服務(wù)四大領(lǐng)域，服務(wù)對象覆蓋全球高校實驗室、科研機構(gòu)、生物醫(yī)藥企業(yè)及診斷試劑開發(fā)商。
經(jīng)過15年技術(shù)積累，AR已建成從抗原設(shè)計與驗證、抗體篩選與表征，到試劑配方開發(fā)、規(guī)?；a(chǎn)的全鏈條技術(shù)平臺。團隊匯聚了分子生物學、免疫學、細胞工程等領(lǐng)域的博士及行業(yè)資深專家，累計申請國際技術(shù)23項，參與發(fā)表SCI論文超120篇，并通過ISO 9001質(zhì)量管理體系認證、FDA cGMP合規(guī)生產(chǎn)標準，確保每一款產(chǎn)品均經(jīng)過嚴格的性能驗證與批次穩(wěn)定性測試。
如今，AR的產(chǎn)品與服務(wù)已觸達全球50余個國家，合作客戶包括哈佛醫(yī)學院、斯坦福大學、MD安德森癌癥中心等頂尖科研機構(gòu)，以及輝瑞、諾華等跨國藥企的研發(fā)部門。我們始終以“客戶需求"為導向，不僅提供標準化產(chǎn)品，更針對前沿研究需求（如單細胞測序、類器官培養(yǎng)、AI輔助藥物篩選等）提供定制化開發(fā)服務(wù)，助力科研人員突破技術(shù)瓶頸。
貨號:16-16-012901
分子量（MW）：70,000
消光系數(shù)：0.703
通過20 mM雙亞氨基三（羥甲基）甲烷（Bis-Tris）緩沖液（pH 6.4，含200 mM NaCl）凍干制得。
儲存條件：≤ -20°C
人血漿α2抗纖溶蛋白（凝血因子）
可有效抑制纖溶酶原激活劑誘導的纖維蛋白凝塊溶解。血漿中濃度約為70微克/毫升。α-抗纖溶蛋白缺乏癥是一種罕見的凝血功能障礙，會導致纖溶活性不受限。此類患者可在術(shù)前接受治療性α2抗纖溶蛋白（A2AP），以預防術(shù)后出血。
純度：≥95%（通過SDS-聚丙烯酰胺凝膠電泳檢測）
活性：≥5.0 單位/毫克
本品由經(jīng)FDA批準檢測顯示HBsAg、抗HCV、抗HBc陰性，且抗HIV 1/2陰性的血漿制備。
Athens Research & Technology產(chǎn)品為實驗室試劑，不可用于人體或作為藥物用途，僅限研究使用。
產(chǎn)品引用文獻：
Zimmerman, Thomas P., Valery Novokhatny, Shan Jiang, and James D. Colandene. "Reversibly inactivated acidified plasmin composition." U.S. Patent Application 13/761,684, filed February 7, 2013.
Singh S, Houng A, Reed GL.
Releasing the Brakes on the Fibrinolytic System in Pulmonary Emboli.
Circulation. 2017 Mar 14;135(11):1011-1020. doi: 0.1161/CIRCULATIONAHA.116.024421. Epub 2016 Dec 27
貨號:K060-H1
人髓過氧化物酶（MPO）酶聯(lián)免疫吸附試驗（EIA）試劑盒 特點：
用途——檢測多種基質(zhì)中的人MPO
樣本類型——血清、無血小板肝素血漿、唾液、尿液或組織培養(yǎng)液
樣本量/盒——40份（重復檢測）
靈敏度——0.068納克/毫升
穩(wěn)定性——液體試劑于4°C下穩(wěn)定保存
快速出結(jié)果——2.5小時內(nèi)完成
髓過氧化物酶（MPO）是一種四聚體含血紅素蛋白，主要由中性粒細胞大量產(chǎn)生，在其中發(fā)揮重要的抗微生物作用。當粒細胞脫顆粒時，MPO會被釋放到細胞外空間。作為中性粒細胞“呼吸爆發(fā)"的一部分，它能通過過氧化氫（H?O?）和氯離子（Cl?）生成次氯酸（HOCl）。此外，MPO還能利用過氧化氫氧化酪氨酸生成酪氨酰自由基。次氯酸和酪氨酰自由基均具有細胞毒性，可有效殺滅細菌及其他病原體。遺傳性髓過氧化物酶缺乏癥會增加個體患免疫缺陷的風險。
研究表明，MPO水平升高與冠狀動脈疾病相關(guān)。2003年有研究提出，MPO可能作為胸痛患者心肌梗死的敏感預測指標。此后，大量文獻（已發(fā)表逾百篇）進一步證實了MPO檢測在心臟病患者中的臨床價值。2010年的補充研究進一步優(yōu)化了這一臨床應用：通過聯(lián)合檢測MPO和C反應蛋白（CRP），相較于單獨檢測CRP，可更精準地預測死亡風險。
參考文獻：
Zhang et al. (2001) Association between myeloperoxidase levels and risk of coronary artery disease; JAMA, 286 2135
Brennan et al. (2003) Prognostic value of myeloperoxidase in patients with chest pain; New Engl. J. Med., 349 1595
Heslop et al. (2010) Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography; J. Am. Coll. Of Cardiol. 55 1102
Athens研究與技術(shù)公司（ART）與Arbor檢測公司合作，推出了目前MPO EIA試劑盒。Arbor檢測公司的創(chuàng)始團隊及頂尖科學家自1982年起便致力于研發(fā)高質(zhì)量檢測試劑盒。ART依托其30年在蛋白質(zhì)純化技術(shù)領(lǐng)域的經(jīng)驗，成功分離出高純度抗原；Arbor檢測團隊在此基礎(chǔ)上，通過抗體配對設(shè)計、精細優(yōu)化及嚴格的質(zhì)量控制（其標志性優(yōu)勢），最終開發(fā)出這款頂級酶聯(lián)免疫吸附試驗試劑盒。經(jīng)驗證，Athens研究與技術(shù)/Arbor檢測人MPO EIA試劑盒適用于血清、無血小板肝素血漿、唾液、尿液及組織培養(yǎng)液樣本，2.5小時內(nèi)即可完成檢測，靈敏度達0.068納克/毫升（注：原文此處可能存在筆誤，前文靈敏度為0.068 ng/mL，末段誤寫為0.68 ng/ml，翻譯保留原文數(shù)據(jù)）。該試劑盒可通過任一合作公司購買（Arbor檢測貨號：K060-H1；Athens研究與技術(shù)貨號：K060-H1）。
分子量（MW）：28,000
消光系數(shù)（Extinction Coefficient）：1.22
冷凍保存于10 mM NH?HCO?緩沖液（pH 7.4）中
儲存條件：≤-70°C
購買純化天然人載脂蛋白AI（ApoA1）（來源于人血漿）。可提供批量采購。
高密度脂蛋白（HDL）中75%的載脂蛋白A為Apo AI。Apo AI水平與冠心病風險呈負相關(guān)。此外，Apo AI被認為可激活卵磷脂膽固醇酰基轉(zhuǎn)移酶（LCAT）。正常血漿中，Apo AI水平范圍為90-130 mg/100 mL。
純度：通過SDS-PAGE檢測≥95%
本產(chǎn)品由經(jīng)FDA批準方法檢測為陰性的血漿制備（乙肝表面抗原[HBsAg]、丙肝抗體[anti-HCV]、乙肝核心抗體[anti-HBc]無反應；人類免疫缺陷病毒1型/2型抗體[anti-HIV 1 & 2]陰性）。
Athens Research & Technology產(chǎn)品為實驗室試劑，不可用于人體或任何藥物用途，僅限研究使用。
產(chǎn)品引用文獻： Soffientini, Ugo, et al. "Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1841.10 (2014): 1372-1382.
Soffientini U, Dolan S, Graham A.
Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis.
Journal of Diabetes and Metabolism, Volume 6, Issue number 588. DOI: 10.4172/2155-6156.1000558.
Winford, Sidney, Moriah Tobin, and Eitan Gross. "Surface-induced assembly of apolipoprotein AI: Implications for symmetry-driven non-cooperative clustering."Journal of Crystal Growth 343, no. 1 (2012): 38-44.
Konno, Shunichi, Masami Tanio, Itsuko Ishii, Kazuhiko Machida, Fumiaki Matsumoto, Kaneshige Satoh, Masayuki Aso, and Yasushi Saito. "Ceiling culture-derived proliferative adipocytes are a possible delivery vehicle for enzyme replacement therapy in lecithin: cholesterol acyltransferase deficiency." Open Gene Therapy Journal 4 (2011): 1-10.
Scharadin TM, et al.
Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.
PLOS One, 2017 Jun 6;12(6).
Prathipati P, Zhu J, Dong X.
Development of novel HDL-mimicking α-tocopherol-coated nanoparticles to encapsulate nerve growth factor and evaluation of biodistribution.
Eur J Pharm Biopharm. 2016 Nov;108:126-135. doi: 10.1016/j.ejpb.2016.08.005. Epub 2016 Aug 12.
技術(shù)深度與廣度兼?zhèn)洌焊采w抗體開發(fā)（多克隆/單克隆/重組抗體）、功能試劑盒（ELISA/Western Blot/流式檢測）、細胞培養(yǎng)（原代細胞/干細胞/類器官培養(yǎng)基）三大核心技術(shù)方向，可滿足從基礎(chǔ)研究到轉(zhuǎn)化醫(yī)學的全流程需求。
嚴格的品控體系：所有產(chǎn)品均經(jīng)過“原料溯源-工藝驗證-性能測試-批次留樣"四步質(zhì)控，關(guān)鍵指標（如抗體親和力、試劑盒靈敏度）的批次間差異率≤5%，確保實驗結(jié)果可重復。
定制化服務(wù)響應快：針對客戶的個性化需求（如新型抗原抗體開發(fā)、特殊物種細胞培養(yǎng)基優(yōu)化），提供“需求溝通-方案設(shè)計-樣品測試-量產(chǎn)交付"的全周期支持，平均定制周期較行業(yè)縮短30%。
全球化的服務(wù)網(wǎng)絡(luò)：在美國、歐洲及亞太地區(qū)設(shè)立倉儲中心，支持48小時內(nèi)緊急訂單發(fā)貨；配備專業(yè)的技術(shù)支持團隊（含中文服務(wù)），為全球客戶提供7×12小時技術(shù)咨詢。
高校/科研院所實驗室：為基礎(chǔ)醫(yī)學、生物學、藥學等領(lǐng)域的師生提供高性價比的研究工具，支持論文發(fā)表與課題申報。
生物醫(yī)藥企業(yè)研發(fā)部：為新藥靶點驗證、藥效評價、臨床前研究提供定制化試劑（如疾病模型動物用抗體、細胞功能檢測試劑盒）。
診斷試劑開發(fā)商：提供高特異性抗原/抗體原料，用于傳染病、腫瘤標志物等體外診斷試劑盒的開發(fā)。
類器官/器官芯片研究團隊：定制化培養(yǎng)基與基質(zhì)膠產(chǎn)品，支持干細胞衍生類器官的高效培養(yǎng)與功能維持。
Q1：AR的抗體在跨物種檢測中表現(xiàn)如何？
A：AR抗體開發(fā)時均經(jīng)過多物種同源性分析，優(yōu)先選擇保守表位設(shè)計抗原，確保在人、小鼠、大鼠等常見物種中具有良好的交叉反應性。若需特殊物種（如兔、猴）檢測，可提供定制化抗原表位設(shè)計服務(wù)。
Q2：定制化產(chǎn)品的交付周期需要多久？
A：常規(guī)定制（如抗體亞型轉(zhuǎn)換）約4-6周；復雜項目（如全新抗原開發(fā)+抗體篩選）約12-16周，具體時間根據(jù)需求復雜度評估后會與客戶確認。
Q3：產(chǎn)品出現(xiàn)質(zhì)量問題如何解決？
A：AR提供“30天無理由退換"服務(wù)（需保留完整包裝與使用記錄）。若因產(chǎn)品質(zhì)量問題導致實驗失敗，經(jīng)技術(shù)驗證后可免費補發(fā)或退款，并安排專人跟進解決。
Q4：是否支持小批量采購？
A：是的，AR提供毫克級抗體、微升級試劑盒及小規(guī)格培養(yǎng)基的采購選項，起訂量可根據(jù)客戶需求協(xié)商調(diào)整，降低中小實驗室的采購成本。
貨號 | 品名 | 規(guī)格 | 品牌 |
01-05-030000-1ML | Anti-Catalase Polyclonal Ab, Human Erthrocyte | 1ml | Athens Research |
12-16-030825-1mg | Chylomicrons, Human Plasma | 1mg | Athens Research |
12-16-120412-5mg | Lipoproteins, Low Density, Human Plasma | 5mg | Athens Research |
12-16-120412-OX-1mg | Lipoproteins, Oxidized, Low Density, Human Plasma | 1mg | Athens Research |
12-16-121601-100ug | Lipoprotein (a), Human Plasma | 100ug | Athens Research |
12-16-121601-1mg | Lipoprotein (a), Human Plasma | 1mg | Athens Research |
12-16-221204-5mg | Lipoproteins, Very Low Density, Human Plasma | 5mg | Athens Research |
16-05-030000-1mg | Catalase, Human Erythrocyte (50 KU per mg) | 1mg | Athens Research |
16-05-030112-P-100ug | Calpain-1, Porcine Erythrocytes | 100 ug | Athens Research |
16-05-030112-P-1mg | Calpain-1, Porcine Erythrocytes | 1 mg | Athens Research |
16-12-030102-25ug | Cathepsin B, Human Liver | 25ug | Athens Research |
16-12-030102-50ug | Cathepsin B, Human Liver | 50ug | Athens Research |
16-12-030104-100ug | Cathepsin D, Human Liver | 100ug | Athens Research |
16-12-030104-25ug | Cathepsin D, Human Liver | 25ug | Athens Research |
16-12-030112-25ug | Cathepsin L, Human Liver | 25ug | Athens Research |
16-13-090701-10mg | Secretory IgA, Human Colostrum | 10mg | Athens Research |
16-13-090701-1mg | Secretory IgA, Human Colostrum | 1mg | Athens Research |
16-13-090701-5mg | Secretory IgA, Human Colostrum | 5mg | Athens Research |
16-13-A20103 | Apolactoferrin, Human Milk | 5mg | Athens Research |
16-14-012621-100ug | Azurocidin, Human Neutrophil | 100ug | Athens Research |
16-14-012621-1mg | Azurocidin, Human Neutrophil | 1mg | Athens Research |
16-14-030107-100ug | Cathepsin G, Human Neutrophil | 100ug | Athens Research |
16-14-030107-50ug | Cathepsin G, Human Neutrophil | 50ug | Athens Research |
16-14-051200-100ug | Elastase, Human Neutrophil | 100ug | Athens Research |
16-14-051200-1mg | Elastase, Human Neutrophil | 1mg | Athens Research |
16-14-130000-100ug | Myeloperoxidase, Human Neutrophil | 100ug | Athens Research |
16-14-130000-1mg | Myeloperoxidase, Human Neutrophil | 1mg | Athens Research |
16-14-130000作廢 | Myeloperoxidase, Human Neutrophil | 100ug | Athens Research |
16-14-161820-100ug | Proteinase 3, Human Neutrophil | 100ug | Athens Research |
16-14-161820-25ug | Proteinase 3 (PR3), Human Neutrophil | 25ug | Athens Research |
16-15-160518-100ug | Eosinophil Peroxidase, Human Eosinophils | 100ug | Athens Research |
16-16-010700-10mg | Alpha 1 Acid Glycoprotein (A1AGP), Human Plasma | 10mg | Athens Research |
16-16-011202-CM-10mg | Albumin, Cynomolgus Monkey ** | 10mg | Athens Research |
16-16-011609-1mg | Alpha 1 Antitrypsin, Human Plasma | 1mg | Athens Research |
16-16-011609-5mg | Alpha 1 Antitrypsin, Human Plasma | 5mg | Athens Research |
16-16-012013-1mg | Alpha 2 Macroglobulin, Human Plasma | 1mg | Athens Research |
16-16-012020-1mg | Antithrombin III, Human Plasma | 1mg | Athens Research |
16-16-012400-1mg | Alpha 1 Antichymotrypsin, Human Plasma | 1mg | Athens Research |
16-16-012901-100UG | Alpha 2 Antiplasmin, Human Plasma | 100ug | Athens Research |
16-16-012901-1MG | Alpha 2 Antiplasmin, Human Plasma | 1mg | Athens Research |
16-16-012901-500UG | Alpha 2 Antiplasmin, Human Plasma | 500ug | Athens Research |
16-16-030402-100ug | C4b-Binding Protein, Human Plasma | 100ug | Athens Research |
16-16-030402-1mg | C4b-Binding Protein, Human Plasma | 1mg | Athens Research |
16-16-030518-1mg | Ceruloplasmin, Human Plasma | 1mg | Athens Research |
16-16-032001-1gram | Transferrin (HOLO), Human Plasma | 1 gram | Athens Research |
16-16-032001-CM-1mg | Transferrin, Cynomolgus Monkey ** | 1mg | Athens Research |
16-16-032001-CM-5mg | Transferrin, Cynomolgus Monkey | 5 mg | Athens Research |
16-16-032001-LEL-1gram | Transferrin (HOLO), Human Plasma, Tissue Culture Grade | 1gram | Athens Research |
16-16-080116-1/1-1mg | Haptoglobin, Phenotype 1-1, Human Plasma | 1mg | Athens Research |
16-16-080116-1mg | Haptoglobin, Human Plasma, Mixed Type | 1mg | Athens Research |
16-16-080116-2/2-1mg | Haptoglobin, Phenotype 2-2, Human Plasma | 1mg | Athens Research |
16-16-080116-5mg | Haptoglobin, Human Plasma, Mixed Type | 5mg | Athens Research |
16-16-080513-LEL | Hemopexin, Low Endotoxin Level, Human Plasma | 1mg | Athens Research |
16-16-081907-1mg | Alpha 2 HS Glycoprotein, Human Plasma | 1mg | Athens Research |
16-16-090109-100ug | Inter Alpha Inhibitor Proteins (IaIp), Human Plasma | 100ug | Athens Research |
16-16-090109-1mg | Inter Alpha Inhibitor Proteins (IaIp), Human Plasma | 1mg | Athens Research |
16-16-090109-25ug | Inter Alpha Inhibitor Proteins (IaIp), Human Plasma | 25ug | Athens Research |
16-16-090701-10mg | Immunoglobulin A1 (IgA1), Human Myeloma Plasma | 10mg | Athens Research |
16-16-090701-1M-10mg | Immunoglobulin A1, Human Myeloma Plasma | 10mg | Athens Research |
16-16-090701-1M-1mg | Immunoglobulin A1, Human Myeloma Plasma | 1mg | Athens Research |
16-16-090701-1M-5mg | Immunoglobulin A1, Human Myeloma Plasma | 5mg | Athens Research |
16-16-090701-1mg | Immunoglobulin A, Human Plasma | 1mg | Athens Research |
16-16-090701-2M-1mg | Immunoglobulin A2, Human Plasma | 1mg | Athens Research |
16-16-090705 | Immunoglobulin E, Human Plasma 1mg | 1mg | Athens Research |
16-16-090705-100ug | Immunoglobulin E, Human Plasma | 100ug | Athens Research |
16-16-090705-M-Lambda-100ug | Immunoglobulin E, Human Myeloma Plasma, Lambda | 100ug | Athens Research |
16-16-090707 | 人免疫球蛋白 | 毫克 | Athens Research |
16-16-090707-1-1mg | Immunoglobulin G1, Human Normal Plasma | 1mg | Athens Research |
16-16-090707-1M | Immunoglobulin G1, Human Myeloma Plasma | 1mg | Athens Research |
16-16-090707-1M-10mg | Immunoglobulin G1, Human Myeloma Plasma | 10mg | Athens Research |
16-16-090707-1M-5mg | Immunoglobulin G1, Human Myeloma Plasma | 5mg | Athens Research |
16-16-090707-2M-10mg | Immunoglobulin G2, Human Myeloma Plasma | 10mg | Athens Research |
16-16-090707-2M-1MG | Immunoglobulin G2 Human Myeloma Plasma | 1mg | Athens Research |
16-16-090707-2M-5mg | Immunoglobulin G2, Human Myeloma Plasma | 5mg | Athens Research |
16-16-090707-4M-1mg | Immunoglobulin G4, Human Myeloma Plasma | 1mg | Athens Research |
16-16-090707-Fc-10mg | Immunoglobulin G, Fc Fragment, Human Plasma | 10mg | Athens Research |
16-16-090707-FC-1mg | Immunoglobulin G, FC Fragment, Human Plasma | 1mg | Athens Research |
16-16-090713-10mg | Immunoglobulin M, Human Plasma | 10mg | Athens Research |
16-16-090713-1mg | Immunoglobulin M, Human Plasma | 1mg | Athens Research |
16-16-090713-BULK | Immunoglobulin M, Human Plasma | 1g | Athens Research |
16-16-090713-M-1MG | Immunoglobulin M (IgM) Human Myeloma Plasma | 1mg | Athens Research |
16-16-090713-Mfc5u-1mg | Immunoglobulin M, Fc5mu, Human Plasma | 1mg | Athens Research |
16-16-110112-50ug | Kallikrein, Human Plasma (frozen) | 50ug | Athens Research |
16-16-110112-CM | Kallikrein, Cynomolgus Monkey Plasma | 50ug | Athens Research |
16-16-110112-RAT-50ug | Kallikrein, Rat Plasma | 50ug | Athens Research |
16-16-110914-L-1mg | Kininogen, Low Molecular Weight, Human Plasma | 1mg | Athens Research |
16-16-120101-1mg | Apolipoprotein AI, Human Plasma | 1mg | Athens Research |
16-16-120101-500ug | Apolipoprotein AI, Human Plasma | 500ug | Athens Research |
16-16-120101-LEL-1mg | Apolipoprotein AI, Human Plasma, LEL | 1mg | Athens Research |
16-16-120200-500ug | Apolipoprotein B, Human Plasma | 500ug | Athens Research |
16-16-120303-1mg | Apolipoprotein CIII, Human Plasma | 1mg | Athens Research |
16-16-120500-1mg | Apolipoprotein E, Human Plasma | 1mg | Athens Research |
16-16-120500-50ug | Apolipoprotein E, Human Plasma | 50ug | Athens Research |
16-16-161200-1mg | Plasminogen, Human Plasma | 1mg | Athens Research |
16-16-161213-L-1mg | Plasmin, Human Plasma (lyophilized) | 1mg | Athens Research |
16-16-161801-1mg | Prealbumin, Human Plasma (Transthyretin) | 1mg | Athens Research |
16-16-180603-250ul | Rheumatoid Factor (IgM), Human Plasma | 250ul | Athens Research |
16-16-A32001-100mg | APO Transferrin, Human Plasma | 100mg | Athens Research |
16-16-A32001-1gram | APO Transferrin, Human Plasma | 1gram | Athens Research |
16-20-201319 | Thrombospondin, Human Platelet | 25ug | Athens Research |
